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Cell Culture Chamber

The QV600 chamber has been designed for surface cultures, such as skin, respiratory epithelium or whole corneas. Additionally, the use of transwells to create a double cavity chamber is ideal for the study of membranes and barrier models.

Is the QV600 system applicable to your project? Contact us to find out!





    The QV600 provides a constant medium surface, positioned to allow the membrane on commercial inserts to sit at this height and provide cell cultures with a continuous perfusion of media as well as exposure to a controlled gaseous environment.

    The QV600 chamber can also be fitted with an alternative insert to create a double cavity chamber ideal for the study of membranes and barrier models.

    KEY BENEFITS

    Users of the QV600 can expect to profit from a number of key benefits associate with the QV600 cell culture chambers:

    • Continuous flow of medium across cell cultures
    • Consistent ALI level within chambers – no risk of cells drying due to evaporation
    • Ports for control of gas within culture
    • Simple fluid level control
    • Sized for commercially available inserts

    SPECIFICATION

    Chamber width 15 mm internal
    Chamber depth 33 mm, minimum depth 12 mm
    Materials Chamber: PDMS
    Tubing: Tygon
    Luers and reservoir bottle: Polypropylene
    Overall dimensions 23 mm height x 37 mm diameter
    Diameter of tubing Inlet: 1/16” ID
    Outlet: 3/32” ID
    Volume of chamber 2 ml running as ALI, 2 x 2 ml with barrier insert
    QV600 with transwell and insert

    QV600 EVIDENCE AND VALIDATION

    The QV600 chamber is currently being used by both academic and industrial labs worldwide, here’s a selection of the published papers that have used QV600 within their research.

    A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers.

    Authors: Giusti, S. et al., 2014.
    Journal: Biotechnology Journal, 9, pp.1175–1184.

    APPLICATIONS

    Commercially available inserts can easily be fitted to the QV600 chambers, giving them great flexibility and a wide variety of applications:

    Surface cultures

    • Cornea
    • Skin
    • Respiratory System

    Barrier models

    • Gut model
    • Blood-Brain Barrier
    • Kidney
    QV600 Starter Kit
    QV600 logo

    STARTER KIT

    The QV600 starter kit contains everything you need to add flow to your experiments (except a peristaltic pump) – 3 chambers, tubing & reservoir bottle to form a complete circuit, holding trays for the complete system and a user guide.

    QV600 MANUAL

    Fill out the form below to download the QV600 Starter Kit User Manual.

      Complete the below contact form to Download the QV600 ALI protocol

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          Contact Us

          Address: Kirkstall, Ltd York House,
          Outgang Lane, York
          North Yorkshire, YO19 5UP

          Phone: + 44 (0) 1709 361 241

          Business Hours: Monday to Friday 9:00am-5:00pm (UK Time)