Scientific Advisory Panel
Saving Lives Through Better Science™
Professor J Malcolm Wilkinson
He was a visiting Lecturer for FSRM, Neuchatel, Switzerland, on the subject of Micro and Nanotechnology in Biomedical Engineering for over 10 years and was appointed as a Visiting Professor in the Department of Biomedical Engineering at Sheffield University in 2019.
Dr Wilkinson is co-author on several papers on in-vitro models of toxicity and a contributing editor of a recently published book on In-Vitro Testing.
We lay a special focus on the use of relevant, human 3D cell culture systems and primary cells in order to simulate the course of an infection as ‘realistically as possible in the petri dish’ and thus gain insights that are not revealed when using 2D cultures or degenerated cell lines. From 2012 to 2019, I worked as an associate professor and deputy director at the Institute of Hygiene and Medical Microbiology at MUI and have a university professorship in infection biology since 2020. Over the years, I have successfully acquired competitive third-party funding (FWF, NIH, ÖNB), have published continuously (48 publications in the last 5 years), am committed to teaching infectiology and immunology, and have a self-designed course on alternatives to animal experiments in biomedical research in the MUI curriculum to teach junior scientists on the opportunities of human-centered models.
Prof Martin J. D. Clift, a Professor of Particle and Fibre Toxicology at Swansea University (SU) Medical School, is globally recognised for using advanced in vitro lung model systems to assess the toxicology of particles and fibres (>165 publications; h-index 38; >5970 citations). His expertise is upon air pollution as well as in vitro systems/(nano)particle and fibre toxicology. His research has focused on in vitro models, incorporating fluid-flow dynamics, that mimic the in vivo environment to gain a mechanistic understanding of how particles/fibres materials may, potentially, be adverse towards human health. He has been/is PI on research projects totalling >£5 million, with a further >£30million as Co-I (since 2011). He is a full member of the UK Government Committee of Medical Effects of Air Pollutants (COMEAP), as well as a member of the Sub-Scientific Committee of the British Toxicology Society (BTS) and a Scientific Board member of Animal Free Research (AfR) UK. He also acts as Editor-in-Chief (Fibers), Senior/Associate Editor (Particle Fibre Toxicology; Journal of Nanobiotechnology) and Editorial Board Member for numerous journals.
Dr. Harvey J. Clewell
Dr. Harvey J. Clewell is a research scientist with over forty-five years of experience in environmental quality and toxicology research, chemical risk assessment and hazardous materials management. He is currently a Principal Consultant with Ramboll US Consulting, Inc. He received a Masters in Chemistry from Washington University, St. Louis, and a PhD in Toxicology from the University of Utrecht, the Netherlands. He is a Diplomate of the American Board of Toxicology and a Fellow of the Academy of Toxicological Sciences. He has gained an international reputation for his work on the incorporation of mechanistic data and mode of action information into chemical risk assessments, having played a seminal role in the use of physiologically based pharmacokinetic (PBPK) modeling in cancer and non-cancer assessments. He has authored more than 200 peer-reviewed scientific publications and book chapters on the use of pharmacokinetics, dose-response analysis, genomics and new alternative methods (NAMs) in risk assessment. In 2007 the Society of Toxicology recognized Dr. Clewell with the Arnold J. Lehman Award for major contributions to chemical safety and risk assessment. He served as a member of the ECVAM Scientific Advisory Committee from 2012 to 2016.
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