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Introducing Quasi Vivo

Quasi Vivo® is an advanced interconnected cell culture flow system, specifically designed to provide a solution to the major problems academic and industry researchers encounter when using conventional in vitro systems and in vivo research.

Quasi Vivo logo


By introducing flow to the in vitro environment, Quasi Vivo® significantly increases the physiological relevance of your research, enabling you to generate more accurate models, greatly improving confidence in the validity of your results.

Significant benefits include:

  • Improved cell viability
  • Close control of multiple variables
  • Flexible and easy to use
  • Time and cost savings
  • Long term culture


The Quasi Vivo® system has different chambers available, each of these have been designed to meet the needs of specific applications.

QV900 Logo

Consists of three biocompatible chambers capable of air-liquid and liquid-liquid interface. Compatible with standard inserts and highly modular for increased flexibility of use.

QV900 Logo
Consists of 6 chambers on a standard multi-well plate footprint and is made from a material with little to none non-specific binding.


Kirkstall’s Quasi Vivo® building block system offers great flexibility when designing your experiments.

Chambers are connected by a dynamic flow of media, transported through the system in tubing attached to chambers.

Quasi Vivo® chambers can be linked in series, allowing for the setup of extensive co-culture models.

QV500 Chamber


When it came to designing the Quasi Vivo® system, as well as delivering significant scientific benefits we’ve also ensured the system is very user friendly.

That’s why we’ve used luer locks to connect chambers to tubing, ensuring all seals are secure and liquid tight, whilst also being very easy to use.


The Quasi Vivo® systems were designed to provide metabolically active cells with ideal oxygen concentrations.

Furthermore oxygen gradients within the chamber can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.

QV500 Chamber


The flow rate of the media is easily adapted by changing the settings on your peristaltic pump to ensure that the media perfuses cells at the correct level.

The chamber geometry ensures low levels of shear stress are applied to cells within the chamber (similar to that of hepatocyte shear stress), whilst using relatively high flow rates as delivered by the pump.

Again your desired level of shear stress can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.


The recirculating media reduces the need for frequent media changes by allowing the cells themselves to condition their own environment and maintain this for over several days.

This leads to reduced perturbation of the system, giving you your weekends back!

Quasi Vivo 600 models


In addition to all of these benefits, Quasi Vivo also provides you with ultimate ease of use and flexibility:

  • Optimum scale for useful outputs
  • Compatible with most scaffolds and gels
  • Compatible with most standard inserts and transwells
  • Fits in standard incubator
  • Powered by standard peristaltic pump
  • Works with any cell type


The Quasi Vivo® is used for a variety of applications in academic and pharmaceutical laboratories around the world

Professor Jamie Davies

(University of Edinburgh, UK)

Professor of Experimental Anatomy and leader of a laboratory in Centre for Integrative Physiology.

Dr Simon A. Whawell

(University of Sheffield, UK)

Reader in Oral Science & Director of Postgraduate Taught Courses. Academic Unit of Oral & Maxillofacial Pathology School of Clinical Dentistry

Dr Miriam Dwek

(University of Westminster, UK)

Reader in Biomedical Sciences, leader of the Cancer Research Group and Research Coordinator for the Department of Biomedical Sciences.

Quasi Vivo®, used in 100+ labs worldwide, getting started is easy and cost effective!


Quasi Vivo® features in many academic publications. View more

Dynamic Fluid Flow Exacerbates the (Pro-)Inflammatory Effects of Aerosolised Engineered Nanomaterials In Vitro

Products: QV600

Authors: Kirsty Meldrum et al., 2022.
Journal: Nanomaterials 2022, 12(19), 3431

 Adaptation of the Kirkstall QV600 LLI Microfluidics System for the Study of Gastrointestinal Absorption by Mass Spectrometry Imaging and LC-MS/MS

Products: QV600

Authors: Chloe E. Spencer et al., 2022.
Journal: Pharmaceutics 2022, 14(2), 364

Placental Villous Explant Culture 2.0: Flow Culture Allows Studies Closer to the In Vivo Situation

Products: QV500

Authors: Nadja Kupper et al., 2021.
Journal: Int. J. Mol. Sci. 2021, 22(14), 7464

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    Contact Us

    Address: Kirkstall, Ltd York House,
    Outgang Lane, York
    North Yorkshire, YO19 5UP

    Phone: + 44 (0) 1709 361 241

    Business Hours: Monday to Friday 9:00am-5:00pm (UK Time)