Why Quasi Vivo®?
Quasi Vivo® is an advanced interconnected cell culture flow system, specifically designed to provide a solution to the major problems academic and industry researchers encounter when using conventional in vitro systems and in vivo research.
SIGNIFICANTLY IMPROVED HUMAN RELEVANCE
Significant benefits include:
- Improved cell viability
- Close control of multiple variables
- Flexible and easy to use
- Time and cost savings
- Long term culture
The Quasi Vivo® system has different chambers available, each of these have been designed to meet the needs of specific applications.
Consists of three biocompatible chambers capable of air-liquid and liquid-liquid interface. Compatible with standard inserts and highly modular for increased flexibility of use.
Kirkstall’s Quasi Vivo® building block system offers great flexibility when designing your experiments.
Chambers are connected by a dynamic flow of media, transported through the system in tubing attached to chambers.
Quasi Vivo® chambers can be linked in series, allowing for the setup of extensive co-culture models.
EASE OF USE
When it came to designing the Quasi Vivo® system, as well as delivering significant scientific benefits we’ve also ensured the system is very user friendly.
That’s why we’ve used luer locks to connect chambers to tubing, ensuring all seals are secure and liquid tight, whilst also being very easy to use.
Furthermore oxygen gradients within the chamber can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.
FLOW RATE & SHEAR STRESS
The chamber geometry ensures low levels of shear stress are applied to cells within the chamber (similar to that of hepatocyte shear stress), whilst using relatively high flow rates as delivered by the pump.
Again your desired level of shear stress can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.
This leads to reduced perturbation of the system, giving you your weekends back!
AND THERE’S MORE…
- Optimum scale for useful outputs
- Compatible with most scaffolds and gels
- Compatible with most standard inserts and transwells
- Fits in standard incubator
- Powered by standard peristaltic pump
- Works with any cell type
QUASI VIVO® USERS
The Quasi Vivo® is used for a variety of applications in academic and pharmaceutical laboratories around the world
Professor Jamie Davies
(University of Edinburgh, UK)
Professor of Experimental Anatomy and leader of a laboratory in Centre for Integrative Physiology.
Dr Simon A. Whawell
(University of Sheffield, UK)
Reader in Oral Science & Director of Postgraduate Taught Courses. Academic Unit of Oral & Maxillofacial Pathology School of Clinical Dentistry
Dr Miriam Dwek
(University of Westminster, UK)
Reader in Biomedical Sciences, leader of the Cancer Research Group and Research Coordinator for the Department of Biomedical Sciences.
Quasi Vivo®, used in 100+ labs worldwide, getting started is easy and cost effective!
Tissue-engineered microenvironment systems for modeling human vasculature
Authors: Anna Tourovskaia, Mark Fauver, Gregory Kramer, Sara Simonson and Thomas Neumann
Journal: Exp Biol Med (Maywood) 2014 239: 1264
A High-Throughput Bioreactor System for Simulating Physiological Environments
Journal: Exp Biol Med (Maywood) 2014 239: 1096
Authors: David Pamies, Thomas Hartung and Helena T Hogberg
Physiology and metabolism of tissue-engineered skeletal muscle
Journal: Exp Biol Med (Maywood) 2014 239: 1203
Authors: Cindy S Cheng, Brittany NJ Davis, Lauran Madden, Nenad Bursac and George A Truskey
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Address: Kirkstall, Ltd York House,
Outgang Lane, York
North Yorkshire, YO19 5UP
Phone: + 44 (0) 1709 361 241
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